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From the Editor
Editor's Note
 
Memory News
Fatty food weighs down muscles and memory
 
Pumping Neurons: Exercise to maintain a healthy brain
The evidence is growing that moderate regular exercise boosts memory and other brain functions and may help prevent age-related declines.
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How Parkinsonís disease affects the mind

It’s not just a movement disorder. Besides causing tremors and other motion-related symptoms, Parkinson’s disease affects memory, learning, and behavior.

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Creative healing: art therapy for Alzheimer's disease and other dementias
As medical science races to cure dementia, storytelling and other creative activities promise a better quality of life for the millions already diagnosed.
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Memory Tip
Medicate Your Memory
Glossary
Global rating scale
 

A global rating scale is a scale used to summarize a patient's cognitive profile based on neuropsychological testing and/or clinical assessment. Two examples are the Global Deterioration Scale (GDS) and the Alzheimer Disease Assessment Scale (ADAS).

Research to evaluate effectiveness of a drug or other treatment is often measured in terms of changes in a global rating scale. For example, in a hypothetical experminent, a number of Alzheimer's patients are each randomly assigned to one of two groups. One group, the experimental group, is assigned to take a new experimental drug. The second, control group, is assigned to take a currently-available drug. At the start of the experiment, both groups have equivalent global ratings on a scale such as the GDS or ADAS. At the end of six months' time, both groups are again assessed in terms of the global rating scale. If the experimental group's scores have declined less than the control group's scores, this would suggest that the new drug may be more effective as a treatment for Alzheimer's disease.


 

by Catherine E. Myers. Copyright © 2006 Memory Loss and the Brain