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From the Editor
Editor's Note
 
Memory News
Fatty food weighs down muscles and memory
 
Pumping Neurons: Exercise to maintain a healthy brain
The evidence is growing that moderate regular exercise boosts memory and other brain functions and may help prevent age-related declines.
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How Parkinsonís disease affects the mind

It’s not just a movement disorder. Besides causing tremors and other motion-related symptoms, Parkinson’s disease affects memory, learning, and behavior.

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Creative healing: art therapy for Alzheimer's disease and other dementias
As medical science races to cure dementia, storytelling and other creative activities promise a better quality of life for the millions already diagnosed.
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Memory Tip
Medicate Your Memory
Glossary
Galantamine
 

Galantamine is a drug used for treatment of the symptoms associated with Alzheimer's disease (AD). It was approved by the US Food and Drug Administration (FDA) in 2001 and is currently marketed in the US (under the trade name Reminyl) by Janssen Pharmaceutica and Ortho-McNeil. Galantamine is extracted from daffodil bulbs.

Galantamine works to increase the level of acetylcholine in the brain. Acetylcholine is a neurotransmitter which is important for learning and memory; one feature of AD is a reduction in brain levels of acetylcholine. Like the other currently-available AD drugs, tacrine (trade name Cognex), donepezil (trade name Aricept), and rivastigmine (trade name Exelon), galantamine is a cholinesterase inhibitor, meaning that it acts to inhibit the enzymes which break down unused acetylcholine; the result is that existing acetylcholine survives longer and is more effective. Additionally, galantamine may work to stimulate the release of new acetylcholine in the brain.

 


 

by Catherine E. Myers. Copyright © 2006 Memory Loss and the Brain